Toxicosis

Polisorb — treatment of toxicosis

The efficiency of Polisorb MP’s use in combination with the conventional complex therapy for treatment of the gestational toxicosis is characterized by the improvement both of the health of the mother and the fetus and contributes to more physiological progress of pregnancy.

  The gestational toxicosis that affects the health of the pregnant woman and the fetus remains one of the most crucial problems of today’s obstetrics. The traditional complex therapy used for treatment of gestational toxicosis includes theurapetic and protective regimen, diet, hypotensive, corticosteroid, antiaggregant, anticoagulative and detoxication therapy. Complexity, invasiveness, high cost and some contraindications impede the use of the efferent methods (hemosorption and plasmapheresis) for treatment of vast number of patients. Thus, we have to seek for new detoxication methods.

  The progress of gestational toxicosis and its complications are associated with growing concentration of endotoxin and middle-weight molecules in the blood that shows the intensity of endogenic toxicosis.

Bad health?

  Hence, in order to decrease the intoxication of pregnant women suffering from the gestational toxicosis, we used the enterosorbent Polisorb for detoxication and sorption therapy due to the vast experience of clinical use of the enterosorption and easy procedure of its application.

  Polisorb is a powder used for preparation of suspension to be ingested. This nonorganic, nonselective and polyfunctional enterosorbent is produced on the basis of finely dispersed silica (silicon dioxide) with particles sized at 0.09 mm. Polisorb is characterized by pronounced sorption, detoxication and antioxidant properties. This medicine binds the endo- and ectotoxins (including the pathogenic bacteria and bacterial toxins) within the intestine lumen and removes them from the body, sorbs the excess bilirubin, urea, cholesterin and lipid complex, as well as metabolites that cause the progress of the endogenic toxicosis.

Be free from toxicosis!

  For the purposes of enteral detoxication and, as consequence, improvement of intrauterine condition of the fetus the enterosorbent Polisorb was used for treatment of the pregnant women of the main group. The medicine was prescribed per os in the form of aqueous suspension in dosage of 150-200 mg/kg of body weight per day during 10-14 days, 1 hour before meal or ingestion of other drugs.

  Proceeding from the results of enterosorption application using Polisorb obtained during our research, the following conclusions can be made:


      1. Polisorb is safe for the health of the pregnant woman.


      2. Medication is not absorbed into the blood, and for this reason, the medicine is safe for children.

  The efficiency of Polisorb use in combination with the conventional complex therapy for treatment of the gestational toxicosis is characterized by the improvement both of the health of the mother and the fetus and contributes to more physiological progress of pregnancy, delivery and postpartum period, positive early neonatal period among the newborn children and to higher Apgar score (8 and higher) vs the newborn children delivered by the mothers suffering from the gestational toxicosis treated using the traditional complex therapy.

Indications


Allergy

The action of POLISORB is that its the smallest particles are surrounded by allergens, link them together and output through the intestines.


Poisoning

POLISORB not only removes the symptoms and cure its cause – removes poisons and toxins from the human body in a natural way, linking them all through the gastro-intestinal tract.


Diarrhea

One gram POLISORB MP can absorb up to five grams of water; in addition, the medication is characterized by extensive surface sorption. Using its You provides elimination not only the symptoms but also the causes of diarrhea.

Why Polisorb?



Safety
POLISORB don’t contains additives and flavorings, so the medication has no toxic effect and doesn’t cause allergies. Medication not absorbed into the bloodstream, and passes through the liver and kidneys, allowing virtually no contraindications. Enterosorbent POLISORB MP has high security, and can assigned to newborn infants and pregnant women.



Efficiency
Sorption surface of POLISORB MP at use the inside is 300 m2/g, that is significantly higher than most available on the Russian and foreign market of enterosorbents. The medication is able to link any harmful substances



Instantaneity
In the treatment, a special role is played by the first few minutes of the disease, when You need to quickly help the sick, remove toxicity, improve overall health. Here again to helps POLISORB MP, which, due to its unique structure, begins to act immediately after it enters the intestine and is able to radically change the situation for a few moments.
Symptoms

Тошнота, рвота

Боль в животе

Диарея

Обезвоживание
The mechanism of action

Harmful substances, such as allergens, toxins and all kinds of pathogenic bacteria provoke the development of diseases and general deterioration of health;

Polisorb, surrounds harmful bacteria in the intestine and removes them from the body;

Polisorb adsorbs toxins and allergens of different sizes, which makes it possible to equally effectively treat poisoning and allergies of various nature of cause;

Polisorb eliminates only harmful substances by retaining beneficial micronutrients, when taken over the course of up to 14 days.

Instruction
How to use POLISORB
What are you need to know about Polisorb
What is POLISORB?
Precautions to be considered

Polisorb should be dissolved in water and then drunk.


The necessary amount of powder should be added to water under continuous stirring to make a neutrally-tasting suspension which is easy to drink. The suspension should always be freshly made and taken 1 hour before or after a meal (when taking concomitant medication: 2 hours before or after taking the other medicine). The prepared suspension should be taken within 24 hours.


Diarrhea, nausea and vomiting treatment: first day Polisorb should be taken 5 times a day every hour, next days 3 times a day distributed over the course of a day until symptomatic relief.


Allergy treatment: Polisorb should be taken 3 times a day for 10-14 days.


Recommended dose:


Body weight


Single dose*


Amount of water per single dose


Recommended daily dose*


11 to 20 kg


1 g


50 ml


3 g


21 to 30 kg


1.5 g


70 ml


4.5 g


31 to 40 kg


2 g


100 ml


6 g


41 to 60 kg


3 g


100 ml


9 g


61 to 80 kg


4 g


150 ml


12 g


> 80 kg


5 g


150 ml


15 g

* 1 g Polisorb is equal to 2 heaped teaspoons (1 teaspoon is equal to 0.5 g Polisorb).

Additional dosage information:

Adults: Average recommended daily dose: 0.1 to 0.2 g per 1 kg body weight

Maximum daily dose: 0.33 g per 1 kg body weight.

Release form: Polisorb 25g

POLISORB is used for the treatment of diarrhea. 

POLISORB is capable of binding substances with any molecular mass, like bacteria, viruses, toxins, allergens, and other poisonous material, respectively.

Children from 1 year to 6 years should take Polisorb in complex with oral rehydration therapy after consultation with doctor.

POLISORB (m stands for medical and p for per oral) is powdered silicon dioxide intended for oral intake as an aqueous suspension. It appears as a white or whitish, odorless powder easy to disperse in water and forming a suspension. 

POLISORB is a non-organic, non-selective yet poly-functional adsorbent on the basis of highly dispersed silicon dioxide (chemical formula SiO2). It has an adsorption capacity of 300 mg/g. Silicon dioxide itself has excellent adsorptive and detoxicating properties.


In the gastrointestinal tract, Polisorb is capable of binding endogen and exogen substances with any molecular mass, including bacteria, viruses, toxins, allergens, and other poisonous material, respectively Polisorb is not disintegrated in the gastrointestinal tract, nor is it metabolised. It simply passes through the body being excreted naturally including all toxins bound during passage.

When suffering from diarrhea drink plenty of water to balance the body’s fluid loss. It is particularly urgent in case of children to replace lost fluids immediately by drinking plenty of water.

Specific attention should be paid to diarrhoea persisting more than 3 days, showing blood contents or causing fever. It is recommended to see a doctor. If you are pregnant or breast-feeding, ask your doctor or pharmacist for advice before taking POLISORB. Do not use Polisorb longer than 30 days. Keep POLISORB out of sight and reach for children!

Do not use Polisorb for children younger than 1 year. Possible side effects when using POLISORB Side effects might occur, although not everybody gets them. Constipation (obstipation) was reported in rare cases. Allergic (-like) reactions were reported in rare cases. The formation of kidney stones containing silicon is very rarely possible in instances of long­term intake of high doses of preparations containing silicon dioxide.


If using POLISORB longer than 14 days, insufficient adsorption of vitamins and calcium may occur. Make sure that adequate fluids are consumed and that you eat a balanced diet which is rich in essential nutrients and vitamins.


Interaction of POLISORB with medicinal products Please do not take any regular medication at the same time as POLISORB. Allow for 2 hours before or after the intake. Check with your doctor whether the action of POLISORB may interact with your prescribed medication.

Do not use POLISORB in case 


• bleeding stomach and duodenal ulcer


• gastrointestinal haemorrhagic disease;


• intestinal atony;


• hypersensitivity against against silicon dioxide

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